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Isntree Isntree C-Niacin Toning Ampoule (Discontinued) - Product image showing packaging and label for comedogenic ingredient analysis
IsntreeSerum

Isntree C-Niacin Toning Ampoule (Discontinued)

Low Risk(2)
39 ingredients1 flagged

The Isntree C-Niacin Toning Ampoule is a concentrated brightening treatment formulated to revitalize dull skin and target hyperpigmentation. Featuring a base of Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract instead of plain water, this ampoule is packed with natural vitamins to provide potent antioxidant protection. With a functional 4% concentration of Niacinamide, it works to strengthen the skin barrier while regulating oil production and smoothing skin texture. The formula is designed to be lightweight and fast-absorbing, making it an easy addition to any layering routine without feeling heavy or greasy. While this specific version has been discontinued, it was highly regarded for its ability to deliver a healthy glow without the irritation often associated with pure ascorbic acid. It remains a benchmark for gentle, vitamin-based brightening for those seeking an even complexion and improved skin radiance.

Our Analysis

Our analysis of the Isntree C-Niacin Toning Ampoule reveals a low comedogenic risk overall, making it a relatively safe choice for most users. The only flagged ingredient is Tocopherol (Vitamin E), which carries a comedogenic rating of 2 out of 5. While pure Vitamin E oil can be thick and potentially pore-clogging for individuals with highly congestion-prone skin, it is usually included in small amounts in water-based ampoules to act as an antioxidant. Given its position in the ingredient list, it is unlikely to cause issues for the majority of acne-prone users.

Skin Type Recommendations

This ampoule is best suited for oily, combination, and dull skin types looking for brightening without heavy oils. The 4% Niacinamide is excellent for acne-prone skin to help regulate sebum. While generally safe, those with extremely reactive or highly congestion-prone skin should patch test due to the inclusion of Tocopherol.

Flagged Ingredients

2
tocopherol

Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(39 ingredients)

Hippophae Rhamnoides Fruit ExtractButylene GlycolWaterPentylene GlycolNiacinamide (4%)GlycerinBetaineAloe Barbadensis Leaf ExtractMelia Azadirachta Flower ExtractMelia Azadirachta Leaf ExtractCucurbita Pepo Fruit ExtractPhysalis Alkekengi Fruit ExtractSodium HyaluronateDipotassium GlycyrrhizateOcimum Sanctum Leaf ExtractBeta-GlucanCurcuma Longa Root ExtractCorallina Officinalis ExtractBrassica Oleracea Italica ExtractCoccinia Indica Fruit ExtractMoringa OleiferaPanthenolAllantoinBioflavonoids3-O-Ethyl Ascorbic AcidSodium PolyacrylateTocopherolPolysorbate 8012-HexanediolEthyl HexanediolAmmonium Acryloyldimethyltaurate/​Vp CopolymerZanthoxylum Piperitum Fruit ExtractPulsatilla Koreana ExtractAmmonium Acryloyldimethyltaurate/Vp CopolymerRead all the geeky details about Niacinamide here >>Read all the geeky details about Glycerin here >>Read all the geeky details about Tocopherol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.