
NIOD Copper Amino Isolate Serum 5%
NIOD Copper Amino Isolate Serum 5% (CAIS5) is a highly concentrated pro-repair, pro-collagen treatment designed to maintain skin health at a fundamental level. Unlike traditional anti-aging serums that target specific signs of aging, this advanced formula focuses on skin longevity and repair using a potent 5% concentration of pure Copper Tripeptide-1. This peptide is naturally found in human plasma and is celebrated for its ability to support wound healing, collagen synthesis, and anti-inflammatory processes. Supported by a complex of Methylglucoside Phosphate and Copper Lysinate/Prolinate, this serum helps to improve skin elasticity, clarity, and overall texture over time. The formula features a lightweight, water-like consistency that absorbs instantly into the skin without leaving any heavy or greasy residue. This makes it an excellent choice for layering in a multi-step routine. Glycerin provides a foundational layer of humectant hydration, ensuring the skin remains supple while the active copper peptides work to remodel the skin’s appearance. For those seeking a high-performance serum that addresses texture and fine lines without the risk of clogging pores, NIOD CAIS 5% offers a sophisticated, science-forward solution.
Our Analysis
Our analysis of NIOD Copper Amino Isolate Serum 5% confirms a Low Comedogenic Risk. The formulation is remarkably clean, intentionally excluding common pore-clogging waxes, heavy oils, and synthetic thickeners that often trigger breakouts in acne-prone individuals. The primary ingredients, including Glycerin and various Copper complexes, are non-comedogenic and water-soluble. With no flagged ingredients found in the list, this serum is considered safe for those who struggle with congestion or active acne. It provides intensive repair benefits and anti-aging support without the typical risk of aggravating acne or causing new comedones.
Skin Type Recommendations
This serum is ideal for all skin types, particularly oily, combination, and acne-prone skin, thanks to its oil-free, water-based texture. Its anti-inflammatory properties are also excellent for sensitive skin. While dry skin types will benefit from the glycerin and copper peptides, they should follow up with a non-comedogenic moisturizer.
Flagged Ingredients
This product does not contain known high-risk comedogenic ingredients.
Want Deeper Analysis?
Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.














