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NIOD NIOD Non-Acid Acid Precursor 15% - Product image showing packaging and label for comedogenic ingredient analysis
NIOD

NIOD Non-Acid Acid Precursor 15%

Low Risk(2)
29 ingredients1 flagged

NIOD Non-Acid Acid Precursor 15% (NAAP) is a sophisticated resurfacing treatment designed for those who want the benefits of chemical exfoliation without the irritation typically associated with direct acids like AHAs or BHAs. Rather than using low-pH acids, NIOD utilizes fermentation technologies and amino isolates to encourage visible radiance and skin renewal. The formula is anchored by Lactococcus Ferment Lysate, a probiotic ingredient that supports the skin’s natural barrier, and Ethyl Linoleate, a precursor to linoleic acid that helps balance the appearance of oily skin. The texture is a lightweight, milky suspension that feels silky upon application and absorbs efficiently without a greasy finish. By targeting surface regularity and signs of aging through precursors rather than direct acids, NAAP respects the skin's moisture barrier while delivering a smoother, more refined complexion. It is an ideal choice for users seeking a high-tech approach to skin texture and clarity while maintaining a healthy skin pH.

Our Analysis

Our analysis of NIOD Non-Acid Acid Precursor 15% reveals a low comedogenic risk profile, making it a relatively safe choice for those prone to congestion. The primary ingredient of concern is sorbitan isostearate, which carries a low comedogenic rating of 2/5. As an emulsifier, it is generally less likely to cause issues than heavier oils or waxes. Notably, the inclusion of Ethyl Linoleate is a positive for acne-prone skin, as it helps supplement essential fatty acids that are often deficient in blemish-prone individuals. Overall, the formula avoids major pore-clogging triggers while delivering advanced resurfacing benefits.

Skin Type Recommendations

This product is excellent for sensitive and acne-prone skin types that cannot tolerate traditional chemical peels. Its low-clog potential makes it suitable for oily and combination skin, while the hydrating glycerin and probiotic lysate support dry skin types. It is a versatile, non-irritating resurfacer for all skin concerns.

Flagged Ingredients

2
sorbitan isostearate

Emulsifier with lower clog potential than Oleate.

MACR Analysis

5-Axis AI-Powered Risk Assessment

Recommendations

This serum is best suited for individuals not prone to fungal acne or severe sensitivity, offering benefits from peptides and yeast extracts.

Good for:

Individuals with normal to combination skin seeking peptide benefits, Those looking for skin hydration and renewal, provided they are not sensitive to the listed actives.

Use with caution:

Individuals prone to fungal acne (Malassezia folliculitis), Those with sensitive skin who may react to Sodium Salicylate or Ethoxydiglycol, Acne-prone skin that is reactive to fungal triggers or mild pore congestion.

Avoid if:

Individuals with diagnosed Malassezia folliculitis, Those with a history of severe reactions to Polysorbates or specific fatty acids.

Tips:
  • Patch test on a small, inconspicuous area before applying to the entire face.
  • Monitor skin for any signs of increased breakouts, redness, or irritation.
  • Use in conjunction with a gentle cleanser and moisturizer to support overall skin barrier health.

Overall Risk Score

Lower is better

38/100
Low-Moderate Risk

Score by Skin Type

Lower is better

Dry42Consider Alt.
Oily45Consider Alt.
Sensitive40Caution
Acne-Prone49Consider Alt.

Same product, different risks based on your skin type

Detected: serum

This leave-on serum presents a moderate overall comedogenic risk, with key concerns revolving around ingredients that may support Malassezia yeast growth and potential barrier disruption. While containing beneficial peptides and extracts, the inclusion of Ethyl Linoleate and Polysorbate 60 warrants caution for fungal acne-prone individuals. The presence of penetration enhancers like Ethoxydiglycol can amplify these risks.

Risk Breakdown

(PR) Plugging Risk2.0/5
(BR) Barrier Risk2.0/5
(FR) Fungal Risk2.0/5
(OR) Oxidation Risk2.0/5
(UR) User-Reported2.0/5

Ingredient Interactions

These ingredients may interact to increase risk beyond their individual scores.

Polysorbate 60 + Ethoxydiglycol+5 pts

Ethoxydiglycol enhances penetration, which can drive Polysorbate 60 (and its potential to feed Malassezia) deeper into the skin and increase its overall impact on the fungal microbiome.

Ethoxydiglycol acts as a solvent and penetration enhancer, potentially increasing the absorption of Polysorbate 60. This synergistic effect could lead to a more pronounced impact on Malassezia yeast and potentially exacerbate fungal acne or lead to increased skin irritation.

Why This Score?

The overall score of 38 is calculated from the weighted sum of the individual axis scores (PR*7 + BR*5 + FR*3 + OR*2 + UR*3). The moderate PR score is due to ingredients like Ethyl Linoleate and Polysorbate 60. The BR score is influenced by Sodium Salicylate and Ethoxydiglycol. FR is the most significant contributor due to Ethyl Linoleate, Polysorbate 60, and Yeast Extract. OR is low as no highly oxidizable ingredients are present. UR reflects the mixed user reports for Polysorbate 60 and the moderate risk associated with Ethyl Linoleate.

Main factors:

  • Fungal Risk (FR) due to Ethyl Linoleate and Polysorbate 60
  • Plugging Risk (PR) due to Ethyl Linoleate and Polysorbate 60
  • Barrier Risk (BR) due to Sodium Salicylate and Ethoxydiglycol

Reducing factors:

  • Leave-on format with moderate concentrations of flagged ingredients (except top 5)
  • Low OR and UR scores for most ingredients
  • Presence of barrier-supporting ingredients like Glycerin and Lecithin

Skin Type Considerations

Oily/Acne-Prone:This product may exacerbate breakouts due to its fungal-supporting ingredients and potential for mild pore congestion. Oily-prone individuals should monitor for increased breakouts.
Fungal Acne-Prone:High caution is advised. Ethyl Linoleate and Polysorbate 60 are known triggers for Malassezia folliculitis. Careful patch testing is essential.
Dry/Sensitive:While containing some potentially irritating ingredients (Sodium Salicylate, Ethoxydiglycol), the overall barrier impact may be moderate. However, sensitive individuals should patch test to assess tolerance, especially considering the penetration enhancer.
AI Confidence: 95%

This analysis uses the Multi-Axis Comedogenic Risk (MACR) system. Results are AI-estimated and cannot account for actual ingredient concentrations. Individual reactions may vary. Consult a dermatologist for personalized advice.

Full Ingredient List(29 ingredients)

Aqua (Water)Lactococcus Ferment LysateGlycerinEthyl LinoleateHydroxyethyl Acrylate/​Sodium Acryloyldimethyl Taurate CopolymerHexanoyl Dipeptide-3 Norleucine AcetateMyristoyl Nonapeptide-3Yeast ExtractSoy Amino AcidsBisabololPseudoalteromonas ExopolysaccharidesLecithinSorbitan IsostearateIsohexadecanePolysorbate 60Polyacrylate Crosspolymer-6Trisodium Ethylenediamine DisuccinateSodium SalicylateCitric AcidSodium ChloridePotassium SorbateSodium BenzoatePentylene GlycolEthoxydiglycolPhenoxyethanolChlorphenesinHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerRead all the geeky details about Glycerin here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.