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Paula's Choice Paula's Choice Resist Omega+ Complex Serum - Product image showing packaging and label for comedogenic ingredient analysis
Paula's ChoiceSerum

Paula's Choice Resist Omega+ Complex Serum

High Risk(19)
50 ingredients7 flagged

Paula's Choice Resist Omega+ Complex Serum is marketed as a concentrated 'superfood' for the skin, designed to strengthen the moisture barrier and restore a healthy, resilient glow. This serum features a unique blend of omega fatty acids, including Linum Usitatissimum (Linseed) Seed Oil, which is rich in essential nutrients to soothe redness and combat dehydration. With its lightweight, milky texture, it absorbs quickly while providing a surge of hydration through Glycerin and skin-smoothing emollients like Diheptyl Succinate. While the brand emphasizes its ability to nourish dull and thinning skin, our deep dive into the formulation reveals a complex profile for those with sensitive or reactive skin. The serum aims to provide a plump, supple finish, making it a popular choice for those targeting signs of aging or environmental damage. However, because it contains several rich botanical oils and thickening agents, its suitability varies significantly depending on your specific skin concerns and pore-clogging sensitivities.

Our Analysis

Our analysis classifies this serum as a high comedogenic risk. The formulation contains Oleic Acid and Agar, both of which carry a high rating of 4/5. Oleic acid can disrupt the skin barrier in oily types, leading to potential blockages, while Agar acts as a film-former that may trap sebum. The inclusion of Chia Seed Oil (3/5) and Olive Oil (2/5) further increases the emollient richness, which is beneficial for dryness but problematic for acne-prone skin. Furthermore, the fatty alcohols present can be triggers for those sensitive to thick, lipid-heavy formulations.

Skin Type Recommendations

This serum is ideal for dry, very dry, and mature skin types that require intense lipid replenishment. However, it is poorly suited for oily, combination, or acne-prone skin. Due to the high-rated comedogenic ingredients like Oleic Acid and Agar, it is likely to cause congestion or breakouts in those with large pores.

Flagged Ingredients

4
oleic acid

Disrupts skin barrier function and induces pore blockage.

4
agar

Derived from algae; retains some iodides and film-forming clogging properties.

3
chia seed oil

High Omega-3s but can oxidize quickly; moderate risk for oily skin.

2
olive oil

High Oleic Acid content (similar to sebum); generally safe but can exacerbate fungal acne (Malassezia).

2
tocopherol

Pure Vitamin E is thick and sticky; safe in small amounts as an antioxidant, but potentially clogging in pure oil form.

2
cetyl alcohol

A fatty alcohol (emollient) that is generally safe, but can be problematic for very sensitive individuals.

2
cetearyl alcohol

Fatty alcohol emollient with low-moderate comedogenicity on its own. However, when combined with Ceteareth-20, the synergistic effect can significantly increase pore-clogging potential (combined rating of 4).

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(50 ingredients)

Water (Aqua)GlycerinDiheptyl SuccinateCandelilla/​Jojoba/​Rice Bran Polyglyceryl-3 EstersLinum Usitatissimum (Linseed) Seed OilLinoleic AcidLinolenic AcidPassiflora Edulis Seed OilSalvia Hispanica (Chia) Seed OilCeramide EopCeramide EosCeramide NpCeramide NsCaprooyl SphingosineOlea Europaea (Olive) Oil UnsaponifiablesCaprooyl PhytosphingosineSodium HyaluronateCholesterolCeramide ApButyrospermum Parkii (Shea) ButterTocopherol (Vitamin E/​Antioxidant)Hydroxyethyl Acrylate/​Sodium Acryloyldimethyl Taurate CopolymerPrunus Domestica Seed OilLauryl LaurateGlyceryl BehenateHydrogenated LecithinSodium PhytateTrehaloseIsohexadecaneSodium Stearoyl LactylateCapryloyl Glycerin/​Sebacic Acid CopolymerXanthan GumCetyl AlcoholTetrahexyldecyl AscorbateAgarGlyceryl StearateCeteareth-25Cetearyl AlcoholBehenic AcidGlyceryl RosinateCitric AcidBenzyl AlcoholEthylhexylglycerinCandelilla/Jojoba/Rice Bran Polyglyceryl-3 EstersTocopherol (Vitamin E/Antioxidant)Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerCapryloyl Glycerin/Sebacic Acid CopolymerRead all the geeky details about Glycerin here >>Read all the geeky details about Tocopherol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.