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Cosmedix Cosmedix Refine Rx - Product image showing packaging and label for comedogenic ingredient analysis
CosmedixRetinol Treatment

Cosmedix Refine Rx

Low Risk(0)
28 ingredients

Cosmedix Refine Rx is a potent resurfacing treatment designed to transform the skin's texture and tone using a concentrated Vitamin A complex. As a high-strength clinical-grade product, it focuses on accelerating cellular turnover to reveal a more youthful and clear complexion. The formula features Retinyl Acetate, a powerful form of Vitamin A that helps minimize the appearance of fine lines, wrinkles, and enlarged pores without the heavy irritation often associated with traditional retinoids. The addition of Hamamelis Virginiana (Witch Hazel) Water provides natural astringent properties, helping to balance oil production and soothe the skin, while Glycerin and Sodium Lactate act as vital humectants to maintain hydration levels during the exfoliation process. This balance ensures that while the skin is being resurfaced, its moisture barrier remains supported. The texture is typically lightweight and liquid-like, absorbing quickly into the skin to deliver active ingredients deep within the pores. For those looking to target stubborn texture issues or signs of aging while maintaining a clear, acne-safe routine, Cosmedix Refine Rx offers a sophisticated, non-clogging solution.

Our Analysis

Our analysis of Cosmedix Refine Rx shows a low comedogenic risk, making it an excellent choice for those prone to breakouts. The formulation is notably free from common pore-clogging heavy hitters like synthetic oils, waxes, or thickeners that often hide in anti-aging treatments. We scanned the full ingredient list and found no flagged ingredients that would typically trigger acne or congestion. The inclusion of Sodium Lactate and Glycerin ensures the formula remains non-greasy, while the Vitamin A complex focuses on clearing out debris rather than adding to it. It is a clean, clinical option for acne-safe skincare.

Skin Type Recommendations

This product is best for oily, combination, and acne-prone skin due to its lightweight, non-comedogenic formula and oil-balancing Witch Hazel. Those with sensitive skin should introduce it slowly due to the high-strength Vitamin A. It is safe for all skin types looking to improve texture without clogging pores.

Flagged Ingredients

No High-Risk Ingredients

This product does not contain known high-risk comedogenic ingredients.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(28 ingredients)

AquaHamamelis Virginiana (Witch Hazel) WaterRetinyl AcetateGlycerinSodium LactateAlcoholSodium PcaRetinolPolysorbate 20GalactoarabinanHydroxyproline (L)SqualaneCassia Angustifolia Seed PolysaccharideSorbitolHelianthus Annuus (Sunflower) Seed OilDimethiconeProline (L)Sodium Hyaluronate (L)Lavandula Angustifolia (Lavender) OilSantalum Album (Sandalwood) OilGlucuronolactone (D)Potassium SorbateCarbomerSodium HydroxymethylglycinateCitric AcidRead all the geeky details about Glycerin here >>Read all the geeky details about Retinol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.