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Paula's Choice Paula's Choice Clinical 1% Retinol Treatment (Discontinued) - Product image showing packaging and label for comedogenic ingredient analysis
Paula's ChoiceRetinol Treatment

Paula's Choice Clinical 1% Retinol Treatment (Discontinued)

Low Risk(0)
58 ingredients

Paula's Choice Clinical 1% Retinol Treatment was a powerhouse formula designed to target advanced signs of aging and stubborn skin concerns. This potent treatment featured a high 1% concentration of pure retinol, supported by a sophisticated blend of antioxidants like Vitamin C and Vitamin E, along with skin-restoring peptides and ceramides. Although this specific version has been discontinued, it remains a gold standard for those seeking to improve the appearance of deep wrinkles, fine lines, and uneven skin tone. The formula utilized dimethicone and glycerin to provide a smooth, lotion-like texture that felt lightweight on the skin, ensuring the high-strength active could be delivered effectively without a heavy or greasy residue. It also included soothing plant extracts like oat and licorice root to help mitigate the potential irritation often associated with high-percentage retinoids. This balanced approach made it a favorite for those looking for transformative results while maintaining a healthy skin barrier.

Our Analysis

Our analysis of the Paula's Choice Clinical 1% Retinol Treatment reveals a Low comedogenic risk level, which is excellent for a high-potency active treatment. We found no flagged ingredients that typically trigger breakouts or clog pores in this formulation. The base consists of water, dimethicone, and glycerin—ingredients known for their safety and compatibility with acne-prone skin. By avoiding heavy waxes and common pore-cloggers, Paula's Choice created a high-strength retinol that allows users to address texture and aging without the fear of inflammatory acne or congestion. It is an exceptionally clean formula regarding pore safety.

Skin Type Recommendations

This treatment is best suited for oily, combination, and normal skin types. Its non-comedogenic profile makes it a safe choice for acne-prone individuals. However, those with very sensitive skin or rosacea should proceed with caution due to the high 1% retinol concentration, which may cause initial redness or peeling.

Flagged Ingredients

No High-Risk Ingredients

This product does not contain known high-risk comedogenic ingredients.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(58 ingredients)

Water (Aqua)DimethiconeGlycerinButylene GlycolIsononyl IsononanoateCastor Isostearate SuccinateGlyceryl StearateC12-15 Alkyl BenzoateDimethicone CrosspolymerPEG-33Polysorbate 20Behenyl AlcoholPEG-100 StearatePentaerythrityl TetraisostearatePolymethylsilsesquioxaneTetrahexyldecyl AscorbateRetinol 1.0%Ceramide 2Palmitoyl Tetrapeptide-7Palmitoyl Hexapeptide-12Sodium HyaluronateDipotassium GlycyrrhizateGlycyrrhiza Glabra Root ExtractAvena Sativa Kernel ExtractArctium Lappa Root ExtractSalix Alba Bark ExtractGlycine Soja SterolsLecithinAllantoinTocopheryl AcetateHydrolyzed Soy ProteinSorbitan LaurateAcetyl Dipeptide-1 Cetyl EsterDisodium EDTAHydroxyethylcellulosePalmitoyl Tripeptide-1Sodium HydroxideTribeheninCaprylyl GlycolEthylhexylglycerinPentylene GlycolPEG-75 Shea Butter GlyceridesPPG-12/​Smdi CopolymerPEG-10 PhytosterolPEG-8 DimethiconePEG-14Magnesium Aluminum SilicateArachidyl GlucosideArachidyl AlcoholSclerotium GumCarbomerPhenoxyethanolBenzoic AcidRetinolPPG-12/Smdi CopolymerRead all the geeky details about Glycerin here >>Read all the geeky details about Retinol here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.