
iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+ is a scientifically advanced, high-performance serum designed to brighten the complexion and reduce the appearance of fine lines and scars. This clinically-proven formula centers around a 15% concentration of L-Ascorbic Acid (Vitamin C), a powerhouse antioxidant that protects against environmental damage while promoting collagen production. Combined with Arbutin and Mushroom Extract, it effectively targets hyperpigmentation and uneven skin tone. The addition of Hyaluronic Acid ensures the skin remains deeply hydrated, while Copper Tripeptide Growth Factors support long-term skin health and rejuvenation. Its texture is incredibly lightweight and fast-absorbing, leaving no greasy or tacky residue behind. This makes it an excellent choice for those who want potent anti-aging and brightening benefits without the heavy feel of traditional creams. Whether you are dealing with post-acne marks, sun damage, or simply looking to revitalize dull skin, this serum offers a sophisticated blend of ingredients that deliver visible results while maintaining a gentle profile for sensitive complexions.
Our Analysis
Our deep-dive ingredient analysis of iS Clinical Super Serum Advance+ yields a LOW comedogenic risk rating. After scanning the full formulation, we found zero flagged ingredients known to clog pores or trigger breakouts. The formula utilizes a clean, water-based delivery system and relies on high-quality actives like Ascorbic Acid and Arbutin. Unlike many anti-aging serums that use heavy oils or synthetic esters to provide slip, this product is formulated to be strictly non-comedogenic. This makes it an exceptionally safe and effective choice for individuals who are prone to congestion or hormonal acne.
Skin Type Recommendations
This serum is highly recommended for all skin types, including oily, combination, and acne-prone. Its lightweight, oil-free texture won't weigh down greasy skin, while Hyaluronic Acid provides essential hydration for dry types. It is particularly beneficial for those with sensitive skin looking to treat hyperpigmentation without the risk of irritation.
Flagged Ingredients
This product does not contain known high-risk comedogenic ingredients.
Want Deeper Analysis?
Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.














