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iS Clinical iS Clinical Youth Serum - Product image showing packaging and label for comedogenic ingredient analysis
iS ClinicalSerum

iS Clinical Youth Serum

Low Risk(0)
45 ingredients

iS Clinical Youth Serum is a high-performance anti-aging treatment designed to deliver immediate smoothing and long-term restorative results. As a premium serum from the renowned medical-grade brand iS Clinical, it focuses on improving skin texture and reducing the appearance of fine lines and wrinkles. Looking at the formulation, we see Caffeine as a standout ingredient, which provides powerful antioxidant benefits and helps to visibly depuff and energize the skin. Glycerin, a classic and effective humectant, ensures the skin stays hydrated by drawing moisture into the deeper layers for a plumped, healthy glow. The inclusion of PVP contributes to a unique filming effect, providing that immediate tightening sensation many users seek in a lifting serum. Because this formula is water-based and avoids heavy oils or waxes, the texture is incredibly lightweight and silky. it absorbs almost instantly into the skin, making it an ideal layer under moisturizer or makeup without any pilling or greasy residue. This serum is a sophisticated choice for those targeting signs of aging while maintaining a clean, breathable complexion.

Our Analysis

Our analysis of the iS Clinical Youth Serum confirms a Low Comedogenic Risk level. We carefully screened the full ingredient list and found no flagged pore-clogging ingredients, such as heavy oils, synthetic esters, or waxes that typically trigger breakouts in acne-prone individuals. The formula is primarily water-based and utilizes safe humectants like Glycerin and performance actives like Caffeine. This makes it an excellent option for users who want clinical-grade anti-aging benefits without the risk of developing congestion or comedones. It is a clean, skin-safe formulation that prioritizes both efficacy and pore health.

Skin Type Recommendations

This serum is highly recommended for all skin types, including oily, combination, and sensitive. Its non-comedogenic and oil-free profile makes it especially safe for acne-prone individuals. Mature skin types will particularly appreciate the firming and smoothing effects, while those with sensitive skin will find the lightweight, water-based formula gentle and non-irritating.

Flagged Ingredients

No High-Risk Ingredients

This product does not contain known high-risk comedogenic ingredients.

Want Deeper Analysis?

Run our MACR (Multi-Axis Comedogenic Risk) analysis to get a comprehensive 5-axis risk assessment. This AI-powered analysis evaluates ingredients for Plugging Risk, Barrier Damage, Fungal Acne Risk, Oxidation Risk, and real-world User Reports — giving you personalized scores for your skin type.

Full Ingredient List(45 ingredients)

WaterPvpCaffeineGlycerinDisodium EdtaHydroxyethylcelluloseCeratonia Siliqua (Locust Bean) GumHydrolyzed CaseinPseudoalteromonas Ferment ExtractHydrolyzed Wheat ProteinHydrolyzed Soy ProteinTripeptide-10 CitrullineTripeptide-1LecithinButylene GlycolXanthan GumCarbomerTriethanolamineCaprylyl GlycolPhenoxyethanolAhnfeltia Concinna ExtractBeta Vulgaris (Beet) Root Extract (Extrait De Racine De Betterave)Haberlea Rhodopensis Leaf ExtractFaex (Yeast) Extract (Extrait De Levure)Acetyl TyrosineProlineHydrolyzed Vegetable ProteinAdenosine TriphosphateErgothioneineSaccharide IsomerateHydrolyzed Wheat Protein/​Pvp CrosspolymerVp/​Dimethylaminoethylmethacrylate CopolymerPhospholipidsTocopheryl AcetateRetinyl PalmitateAscorbyl PalmitateAsiaticosideAsiatic AcidMadecassic Acid12-HexanediolHydrolyzed Wheat Protein/Pvp CrosspolymerVp/Dimethylaminoethylmethacrylate CopolymerRead all the geeky details about Glycerin here >>[more]

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Our analysis is powered by AI and backed by extensive research on comedogenic ingredients — but it's not medical advice. For skin concerns, please consult a dermatologist.